Why not try it as a first line or last line of defense? There are very few side effects that may be easily managed. One is that high dose Vit C causes copper depletion over time. Copper is used by the body, in conjunction with IV vit C to detox the liver and is used in a reaction that produces peroxides or super oxidants in the blood. The superoxidant is the neat killer of damaged cells that have no defense against the peroxide. These damaged cells are the selective target of the IV vit c.